WebAnywhere is a web-based screen reader for the web. It requires no special software to be installed on the client machine and, therefore, enables blind people to access the web from any computer they happen to have access to that has a sound card. No $1000 software program required!You might want to try this alpha release here (online, no installation needed). I have tested and the result is great, except that it won't read iframe currently. The speech engine is clear for almost every words.
WebAnywhere's will run on any machine, even heavily locked-down public terminals, regardless of what operating system it is running and regardless of what browsers are installed.
This project is now hosted at Google Code, so you can download the source, play with it, and contribute to the project.